Beta Boxes Complex

Beta Boxes Complex

Glove box complex for the handling of radiopharmaceuticals based on beta-emitters

The Beta Boxes Complex is for the handling of Y-90-compounds and other high-energy beta-emitter. It is designed for the GMP-compliant preparation, process and dispensing of Y-90-radiopharmaceuticals up to 30 GBq. The Beta Boxes Complex consists of three interconnected acrylic glass boxes with glove ports. Inward/outward transfer and transfer between the boxes are realised by double locks. Laminar air flow ensures grade A respectively B conditions inside the complex for all the critical process stages.

The operator is supported by local shieldings and manipulation equipment to optimize handling and to essentially reduce radiation exposure, especially to the hands.

We will customize the design and all dimensions of the Beta Boxes Complex on your request regarding your intended process and/or your physical conditions.

 

Technical Data

Dimensions

Outer dimensions (WxDxH)             ca. 1200x1500x3000 (±30) mm

Inner dimensions Box 1 (WxDxH)    ca. 1200x900x600 mm

Inner dimensions Box 2/3 (WxDxH) ca. 900x900x600 mm

 

Weight                                               ca. 1000 kg                                                   

 

Material

Boxes                                                  PMMA, glued

Thickness                                           20 mm

 

Shielding

On all sides                                         20 mm PMMA gegen b^--Strahlung

 

Tightness

Inner cell                                            leak rate < 0.25 %/h according DIN 25412-2

 

Ventilation system

In-air                                                   H13 filter, port DN 50

Exhaust-air                                         H13 filter with charcoal, port DN 50

Laminar air flow                                  Fan, H14 filter, laminator, perforated plates

Negative pressure adjustment           manually operated ball valves

Air monitoring system                         differential pressure, LAF velocity

 

Transfer system / sluices

Inward/outward transfer                     double locks made of stainless steel

Between boxes                                  double lock made of stainless steel

 

Glove ports

Box 1                                                  4 pcs / 4 blank flanges

Box 2/3                                               2 pcs / 2 blank flanges

 

Electrical / pneumatical specification

Electrical connection                         3x230/400 V 50 Hz N/PE, 16 A pre-fuse

Consumption                                      approx. 1 kW

sockets                                               4 pcs each box (IP54), external switchable

                                                           2 pcs above and underneath the boxes

Compressed air                                 > 6 bar

 

Covering

Material                                              powder-coated steel plates

Colour                                                clean white (RAL 9010) or according to customers‘ request

 

Optional

Customised dimensions

Integrated dose rate monitoring system

Integrated dose calibrator

Local shieldings made of lead, acrylic glass or lead glass