synthesis modules
Hot cell for the operation of automated synthesis modules
The mini cell is especially designed for the operation of customary PET synthesis modules or hot cells adapted for research or nuclear medical purposes. The GMP-compliant design ensures the quality of production conditions.
There are four different types, Type I, Type II, Type III and Type IV. The standard model consists of a stainless steel cell and 75 mm lead shielding. A shielded door with an optional lead glass window is implemented at the front side for easy access to the synthesis module.
Customizable design of the mini cell and the thickness of the shielding for customer intended process and/or physical conditions.
Also available are special solutions for the handling of Ga-68 which include coating the inner cell with polyethylene for handling hydrochloric acid.
Technical Data
Dimensions/Weight
| Inner dimensions (WxDxH) | Outer dimensions (WxD) | Height | Weight kg | |
| Typ I | 700x560x775mm | 920x850 mm | 3000 mm | approx. 3.500 kg |
| Typ II | 700x640x775mm | 920x930 mm | 3000 mm | approx. 3.800 kg |
| Typ III | 850x640x775mm | 1070x930 mm | 3000 mm | approx. 4.500 kg |
| Typ IV | 700x500x610mm | 920x770 mm | 3000 mm | approx. 6.000 kg |
| Material | Inner cell stainless steel (1.4301) |
| Shielding | At all sides 75 mm of lead |
| Door | |
| Implementation Left or right hinged swinging door | |
| Lead glass window | 145 x 145 mm, 75 mm of lead-equivalent |
| Tightness | Inner cell leak rate < 0.25 %/h |
| Ventilation system | |
| In-air | H13 filter, port DN 25 |
| Exhaust-air | H13 filter with charcoal, port DN25 negative pressure |
| adjustment | Manually operated ball valves |
| Air monitoring system | Differential pressure |
| Electrical / pneumatical specification | |
| Electrical connection | 3x230/400 V 50 Hz N/PE, 16 A pre-fuse |
| Consumption | approx. 1 kW |
| Sockets | 2 pcs inside (IP54), external switchable 2 pcs above and underneath the cell |
| Compressed air | > 6 bar |
| Covering | |
| Material | Powder-coated steel plates |
| Colour | Clean white (RAL 9010) or according to customers‘ request |
Options
- Customized Dimensions and height of covering
- Slideable tray for synthesis modules
- Fittings and ducts for gas lines
- Double mini cell vertically or horizontally arranged
- Laptop mount
- Shielded feed-through of nuclides
- Storage box for radioactive waste
- Shielded generator storage under the cell with sealed fitting to the inner cell
- Especially for Ga-68: Acid resistant polyethylene coating of the inner cell
research cell
Hot cell for research on PET-radiopharmaceuticals
This research hot cell is designed for the development of new radiopharmaceuticals based on short-lived positron-emitters. It is used for the implementation of fully- or semi-automated synthesis devices for PET-radiopharmaceuticals. The set up is especially suitable for PET centres which provide daily routine products, like FDG, on the one hand, and on the other hand carry out innovative research activities, for example on 68Ga based radiopharmaceuticals. The cell is offered as a single hot cell or in combination with other hot cells as a functional complex.
We are happy to customize the design and all dimensions of the research cell on request for your intended process and/or physical conditions.
We offer a special solution for the handling of 68Ga featuring acid resistant coating of the inner cell with polyethylene and a shielded generator storage under the hot cell.
Optionen auf Anfrage
• Anpassung der Abschirmung zw. 20 bis 100 mm und des Strahlenschutzfensters in Größe und Stärke
• Zusätzliches Hubelement als Rückwand, auch mit Strahlenschutzfenster
• Schleuse für inaktives Material
• Bodenschleuse oder Produktcontainerkasten zur Ausschleusung des Radiopharmakons
• Integriertes Dosisleistungsmesssystem
• Einbau eines Aktivimeters in den Zellenboden
Technical Data
| Dimensions | |
| Outer dimensions (WxDxH) | approx. 1400x1400x2600 (±30) mm |
| Inner dimensions (WxDxH) | approx. 1000x1000x800 mm |
| Weight | approx. 9000 kg |
| Material | Inner cell stainless steel (1.4541) |
| Shielding | |
| Sides, front and back | 75 mm of lead |
| Ceiling and bottom | 75 mm of lead |
| Door / lifting element | |
| Implementation | Electromechanical lifting door, at front side |
| Control | Two-hand safety control |
| Lead glass window | 300 x 300 mm, 100 mm lead-equivalent |
| Tightness | |
| Inner cell | Leakage <0.25 %/h acc. to ISO10648-2 class 2 |
| Ventilation system | |
| In-air | H13 filter, DNport 50 |
| Exhaust-air | H13 filter with charcoal, port DN 50 |
| Negative pressure adjustment | Manually operated ball valves |
| Air monitoring system | Differential pressure |
| Electrical / pneumatical specification | |
| Electrical connection | 3x230/400 V 50 Hz TN-S, 16 A pre-fuse |
| Consumption | approx. 1 kW |
| Sockets | 4 pcs. inside (IP54), external switchable |
| 2 pcs. above and below the cell | |
| Compressed air | > 6 bar |
| Covering | |
| Material | Powder-coated steel plates |
| Colour | Pure white (RAL 9010) or according to customers‘ request |
Options
- Shielding up to 100 mm of lead and customization of lead glass window on request
- Additional lifting element on the back side of the cell, also with lead glass window possible
- Double-door lock for inactive material
- Double-door lock in the bottom or shielded product storage
- under the hot cell to lock out of the radiopharmaceuticals
- Integrated dose rate monitoring and dose calibrator
- Especially for 68Ga: Acid resistant polyethylene coating of the inner cell
Shielded generator storage under the cell with sealed fit to the inner cell
